KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
10.3
Human Site:
S48
Identified Species:
16.19
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
S48
L
G
G
A
G
G
G
S
S
R
H
E
K
S
L
Chimpanzee
Pan troglodytes
XP_511025
426
45548
P34
V
Y
P
P
P
G
T
P
S
R
H
E
K
S
L
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
S48
L
G
G
A
G
G
G
S
S
R
H
E
K
S
L
Dog
Lupus familis
XP_853833
304
33793
L24
L
T
R
S
N
L
G
L
G
S
H
A
V
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
S38
S
R
R
S
R
G
G
S
S
R
H
E
K
S
L
Rat
Rattus norvegicus
Q62814
300
33206
A24
F
V
S
L
L
Q
E
A
Q
D
G
V
L
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
Chicken
Gallus gallus
Q90977
403
43534
K102
G
A
K
S
P
G
E
K
S
R
Y
E
T
S
L
Frog
Xenopus laevis
NP_001086706
375
40890
K24
S
L
G
L
L
T
S
K
F
V
S
L
L
Q
E
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
V25
G
L
L
T
T
K
F
V
T
L
L
Q
E
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
R252
S
S
S
S
S
G
D
R
N
R
A
D
T
S
L
Honey Bee
Apis mellifera
XP_624285
300
34327
L24
T
T
R
F
V
T
L
L
Q
K
A
K
D
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
A45
K
Q
A
A
D
T
L
A
V
R
Q
K
R
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
G128
N
P
S
T
P
V
G
G
C
R
Y
D
S
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
S165
I
T
L
T
P
S
G
S
C
R
Y
D
S
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
53.3
100
26.6
N.A.
66.6
6.6
N.A.
0
40
6.6
0
N.A.
26.6
0
N.A.
13.3
P-Site Similarity:
100
60
100
40
N.A.
73.3
13.3
N.A.
0
53.3
6.6
26.6
N.A.
46.6
20
N.A.
40
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
26.6
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
20
0
0
0
14
0
0
14
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
7
0
0
7
0
20
7
7
0
% D
% Glu:
0
0
0
0
0
0
14
0
0
0
0
34
7
0
7
% E
% Phe:
7
0
0
7
0
0
7
0
7
0
0
0
0
0
0
% F
% Gly:
14
14
20
0
14
40
40
7
7
0
7
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
7
0
7
0
0
7
0
14
0
7
0
14
27
0
7
% K
% Leu:
20
14
14
14
14
7
14
14
0
7
7
7
14
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
0
0
0
7
0
0
0
0
7
0
% N
% Pro:
0
7
7
7
27
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
7
0
0
14
0
7
7
0
7
0
% Q
% Arg:
0
7
20
0
7
0
0
7
0
60
0
0
7
7
0
% R
% Ser:
20
7
20
27
7
7
7
27
34
7
7
0
14
54
0
% S
% Thr:
7
20
0
20
7
20
7
0
7
0
0
0
14
0
0
% T
% Val:
7
7
0
0
7
7
0
7
7
7
0
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _